> CLINICAL RESULTS
> BIOCIDAL ACTION
Virucidal activity against enveloped viruses (1)
Test reference: European standard NF EN 14476+A2
Result: Eliminatation of more than 99.9% of envelopped viruses like coronavirus, herpes simplex virus, influenza virus or HIV in 30 seconds (1)
Bactericidal activity (2)
Test reference: European standard NF EN 13727+A
Result: Elimination of more than 99.9% of bacteria in30 seconds (2)
Yeasticidal activity (3)
Test reference: European standard NF EN 1362
Result: Elimination of more than 99.9% of yeast in 30 seconds (3)
> EFFICACY ON SKIN BARRIER FUNCTION
After 14 days of use, under normal conditions and 10 applications per day on forearms, the skin barrier function reinforcement effect was measuring by the Trans Epidermal Water Loss (TEWL). The results showed that Biphase Lipo alcoolique reduces the TEWL by 22.6% * after 14 days (4). Therefore, it reinforce the skin barrier.
The nourishing effect of Biphase Lipo alcoholic was assessed by measuring the fatty film left on the skin surface. The measurement is made 15 min after one application on the forearm. Under these study conditions, Biphase Lipo alcoolique demonstrated a nourishing effect illustrated by the presence of a residual oily film on the skin’s surface at Timm and T15min compared to T0 (5)
* p ≤ 0.05; Student test, after 14 days
> PATIENTS FEEDBACKS
80% of the patients thought that the product meets the expected properties for a hand sanitizer(6). The product was appreciated for its spray packaging, its ease of spreading, its nourishing effect, and its ability not to dry up the skin. (6)
The Biphase Lipo Alcoolique was considered “non-irritating” after being applied pure on the back of 22 subjects aged 21-69 under semi-occlusive patch during 24h. (7)
(1)Evaluation of the virucidal activity in vitro of Biphase Lipo Alcoolique on enveloped virus to the European standard test EN 14476+A2 in clean conditions – France. 2020
(2)Evaluation of the bactericidal activity of Biphase Lipo Alcoolique on bacteria according to the European standard test EN 13727+A2 in clean conditions – France. 2020
(3)Elimination of the bactericidal activity of Biphase Lipo Alcoolique on bacteria accoridng to the European standard test EN 13727+A2 in clean condition – France. 2020
(4)Evaluation and comparison of the skin barrier reinforcement of Biphase Lipo Alcoolique by measuring the trans epidermal water loss (TEWL) – 20 volunteers (aged 19-61 years old) with 10 applications per day on forearms. France 2020.
(5)Evaluation of the nourishing effect of Biphase Lipo Alcoolique by measuring the residual oily film (aged 22-43) – during 15 min after 1 application on the forearm
(6)User test - evaluation of the cutaneaous safety and acceptability of Biphase Lipo alcoolique with a frequency of use of 10 times per day – 20 volunteers (aged 23-54 years old). France. 2020
(7)Evaluation of the tolerance and acceptability of Biphase Lipo Alcoolique with a single patch test with application on the back – 22 volunteers (aged 21-69 years old) after one application. Poland. 2020
