Recent scientific discoveries have highlighted the importance of the skin microbiome in wound healing. In clinical practice, the inappropriate use of antiseptics can alter the microbiome, resulting in delayed healing due to microbiome unbalanced. Therefore, in order to preserve the healing process, it is important to limit the use of antimicrobial agents and only use them when they are essential. For example, during the wound cleansing stage after an injury, to limit any risk of pathogen colonization. Once this stage has been completed, the use of such antimicrobial agents is no longer necessary and may even be detnd may even be detrimental to the healing process.