Jean, 63 years old, Facial rash
Written with the participation of FDVF (Future Dermatologists and Venereologists of France) interns.
Related topics
- Other
 
- 63-year-old male
 - Facial rash against a background of inflammation
 - Vesicles, pustules, meliceric crusts
 - Progressing for 5 days, sudden onset
 - No pruritus, but pain and a burning sensation
 - Intraoral lesions
 - Impairment of quality of life: hard to eat!
 - Pristinamycin 48 hrs: no improvement
 - Healthy family and friends
 - No animals at home
 - No particular family history
 
Quiz
15 respondents
Question of 1
What is your diagnosis? (only one correct response)
Shingles
Shingles
It is indeed shingles.
Let’s rule out differential diagnoses:
- Acute, sudden and rapidly spreading: not suggestive of a cutaneous tumoural disease.
 - No tumoural appearance
 - Vesicular primary lesion
 - Inflammatory background
 - Meliceric crusts
 - Metameric pattern +++: key factor in the diagnosis (≠ acute impetiginised eczema)
 - No oedema and diffuse pronounced erythema, no increase in local skin temperature, no fever: no arguments in favour of erysipelas BUT possible progression if secondary infection is not treated.
 
Ulcerated basal cell carcinoma
Wrong answer!
It was shingles.
Let’s rule out differential diagnoses:
- Acute, sudden and rapidly spreading: not suggestive of a cutaneous tumoural disease.
 - No tumoural appearance
 - Vesicular primary lesion
 - Inflammatory background
 - Meliceric crusts
 - Metameric pattern +++: key factor in the diagnosis (≠ acute impetiginised eczema)
 - No oedema and diffuse pronounced erythema, no increase in local skin temperature, no fever: no arguments in favour of erysipelas BUT possible progression if secondary infection is not treated.
 
Acute impetiginised eczema
Wrong answer!
It was shingles.
Let’s rule out differential diagnoses:
- Acute, sudden and rapidly spreading: not suggestive of a cutaneous tumoural disease.
 - No tumoural appearance
 - Vesicular primary lesion
 - Inflammatory background
 - Meliceric crusts
 - Metameric pattern +++: key factor in the diagnosis (≠ acute impetiginised eczema)
 - No oedema and diffuse pronounced erythema, no increase in local skin temperature, no fever: no arguments in favour of erysipelas BUT possible progression if secondary infection is not treated.
 
Erysipelas
Wrong answer!
It was shingles.
Let’s rule out differential diagnoses:
- Acute, sudden and rapidly spreading: not suggestive of a cutaneous tumoural disease.
 - No tumoural appearance
 - Vesicular primary lesion
 - Inflammatory background
 - Meliceric crusts
 - Metameric pattern +++: key factor in the diagnosis (≠ acute impetiginised eczema)
 - No oedema and diffuse pronounced erythema, no increase in local skin temperature, no fever: no arguments in favour of erysipelas BUT possible progression if secondary infection is not treated.
 
- Context: Non-immunocompromised male in his sixties
 - Primary lesions:
- Vesicles, grouped in clusters
 - Pustules
 - Erythematous inflammatory background
 
 - Secondary lesions:
- Meliceric crusts = secondary infection
 - Erosions on the oral mucosa
 
 - Location/Pattern:
- Key factor in the diagnosis +++
 - Face: skin AND oral mucosa
 - Unilateral metameric pattern, along the V2 nerve
 
 - Associated signs:
- Pain: neuropathic; often starts before the eruption
 - No pruritus
 - No fever but adenopathy may be found in the drainage region
 
 
- When faced with a painful, vesicular, unilateral and metameric dermatosis, evoke the diagnosis of shingles
 - Facial shingles: investigate mucosal involvement (oral: V2, ocular: V1)
 - HIV serology: testing recommended in at-risk subjects
 
Antiviral treatment (oral valaciclovir or famciclovir, intravenous aciclovir):
- Immunocompetent patients over the age of 50 within 72 hours following the onset of the rash (prevention of postherpetic pain)
 - Ocular shingles
 - Immunocompromised patients
 
Systematic local care:
- Cleansing of the lesions with water and mild soap
 - Repair cream: after the secondary infection, to promote healing
 
Systematic symptomatic treatment:
- Grade I or II analgesics
 - +/-amitriptyline
 
Treating the secondary infection:
- Antibiotic therapy: amoxicillin-clavulanic acid, pristinamycin, macrolide
 - Local antisepsis
 
Treating postherpetic pain:
- Grade II or III analgesics
 - Lidocaine plaster
 - Analgesic psychotropic agents (amitriptyline, carbamazepine, gabapentin, pregabalin, etc.)
 
Preventive treatment = vaccination:
- Recommended for adults aged 65 to 74
 - Reduces the incidence and severity of shingles and postherpetic pain
 
Parent education:
- Vaccination: prevention
 - Hygiene: cleanse the lesions on a daily basis and disinfect to limit infectious complications
 - Do not touch or pick at the lesions
 - Initiate antiviral treatment as soon as possible
 - Suitable nutrition in the event of oral mucosal involvement:
 - cold, puréed/semi-solid foods
 - small, frequent meals
 - local anaesthetics on mucosal lesions before meals
 
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